Molecular characterization of highly gentamicin-resistant Enterococcus faecalis isolates lacking high-level streptomycin resistance
نویسندگان
چکیده
منابع مشابه
Assessment of pheromone response in biofilm forming clinical isolates of high level gentamicin resistant Enterococcus faecalis.
Twenty five clinical isolates of high level gentamicin resistant Enterococcus faecalis were tested for their biofilm formation and pheromone responsiveness. The biofilm assay was carried out using microtiter plate method. Two isolates out of the 25 (8%) were high biofilm formers and 19 (76%) and four (16%) isolates were moderate and weak biofilm formers respectively. All the isolates responded ...
متن کاملGenetic characterization of high-level gentamicin-resistant strains of Enterococcus faecalis in Iran.
The prevalence of resistance to high levels of gentamicin among 182 isolates of Enterococcus faecalis from 2 Iranian hospitals was 42%. Gentamicin resistance was associated with conjugative plasmids (>70 kb) in most strains. Fingerprinting using EcoRI and HindIII showed genetic variation among these plasmids and gave evidence of nosocomial outbreaks and persistence of infection in different war...
متن کاملPrevalence of high-level gentamicin-resistant Enterococcus faecalis and Enterococcus faecium in an Iranian hospital
This study was designed to determine the molecular characteristics and antimicrobial resistance of enterococcal strains isolated from patients admitted to an Iranian Hospital. Enterococcal strains were isolated from the burn patients. All strains were screened for genes encoding resistance to aminoglycoside [aac(6')-Ie-aph(2'')-Ia, aph (3'), ant (4')], resistance to vancomycin (vanA, vanB), res...
متن کاملhigh level resistance of enterococcus faecium and e. faecalis isolates from municipal sewage treatment plants to gentamicin
background: enterococci are members of the normal gut flora and released into the environment via sewage outlets, where they can survive for long times. infections with high-level gentamicin resistant (hlgr) enterococci are emerging worldwide. hlgr enterococci have developed a resistance to most antibiotics commonly used for enterococcal infections therefore; treatment of infections caused b...
متن کاملTreatment of high-level gentamicin-resistant Enterococcus faecalis endocarditis with daptomycin plus ceftaroline.
A recurrent case of left-sided endocarditis caused by high-level aminoglycoside-resistant Enterococcus faecalis was successfully treated with ceftaroline and daptomycin. This combination demonstrated excellent synergy in vitro. Mechanistically, ceftaroline enhanced binding of daptomycin to the cell membrane and sensitized E. faecalis to killing by human cathelicidin LL-37, a cationic innate hos...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1993
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.37.1.134